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Raf kinase inhibitor protein

The RAF kinase inhibitor protein kinase inhibitor protein that regulates many signaling pathways inside the cell. RKIP is a member of the phosphatidylethanolamine-binding protein family and demonstrated destructive position on RAF-1-MEK1 / 2, ERK ...

                                               

Rho kinase inhibitor

Inhibitors of RHO-kinases are a series of compounds that target RHO-kinase. Clinical trials have established that inhibition of the rock pathway contributes to the cardiovascular effects of statin therapy. In addition, inhibitors of rock may have ...

                                               

Ro-318220

                                               

Phosphoinositide 3-kinase inhibitors

                                               

Glutamate decarboxylase inhibitors

                                               

Aldose reductase inhibitor

Their goal aldose-reductase, the enzyme which normally is present in many other parts of the body, and catalyzes one of the steps on the way sorbitolpolyol that is responsible for fructose formation from glucose. Aldose-reductase activity increas ...

                                               

Bacterial dihydrofolate reductase inhibitors

                                               

Fungal dihydrofolate reductase inhibitors

                                               

Protozoal dihydrofolate reductase inhibitors

                                               

AMPT

Alpha-methyl - p -tyrosine hydroxylase inhibitor APF. Alpha-methyl - p -tyrosine is an endogenous drug involved in the biosynthesis of catecholamines way. AMPT inhibits tyrosine hydroxylase whose enzymatic activity is regulated by different Serin ...

                                               

Amifloxacin

                                               

Difloxacin

Difloxacin sold under the brand name Dicural, second generation, synthetic fluoroquinolone antibiotic used in veterinary medicine. He is broad-spectrum, concentration-dependent, bactericidal activity, however, its efficiency is not as good as enr ...

                                               

Fleroxacin

Fleroxacin is a bactericidal drug that inhibits bacterial DNA gyrase and topoisomerase IV. Like other chinolone mixture and fluoroquinolones eradicate bacteria by inhibiting DNA replication. Fleroxacin is active against many gram-positive and Gra ...

                                               

Farnesyltransferase inhibitor

The farnesyltransferase inhibitors are a class of experimental cancer drugs that target protein farnesyltransferase entails the prevention of the normal functioning of the RAS, which are commonly abnormally active in cancer.

                                               

GABA transaminase inhibitor

Pharmacology inhibitor of GABA transaminase is the enzyme inhibitor that acts on GABA-transaminase. Inhibition of GABA-transaminase enzymes, reduces the degradation of GABA, which leads to increased concentration of neuronal GABA. Examples includ ...

                                               

Aminooxyacetic acid

Aminooxyacetic acid, often abbreviated AoA or AOAA, is a compound that inhibits 4-aminobutyrate aminotransferase activity in vitro and in Vivo, leading to less gamma-aminobutyric acid apart. Subsequently, GABA levels increased in the tissues. In ...

                                               

PARP inhibitor

PARP inhibitors are a group of pharmacological inhibitors of the enzyme Poly-ADP-ribose polymerase. They are developed for multiple indications, including treatment of hereditary cancer. Some types of cancer are more dependent on the PAP than reg ...

                                               

Arabinosyl nucleosides

Arabinosyl nucleoside derivatives nucleoside. They contain – in contrast to most nukes – instead of β - D -Ribofuranose in β - D -Arabinofuranose. They are mainly used as cytostatics or virostatics.

                                               

Carbocyclic nucleoside

Carbocyclic nucleoside analogues are nucleosides in which a methylene group replaced by an oxygen atom in the ring furanose. These analogs have a simple nitrogen attached to alkyl carbon, and not to be part of a hemiaminal ester bond. As a result ...

                                               

Cytidine

Cytidine nucleoside molecule that is formed when cytosine is attached to a ribose ring via a β-n-1 glycosidic bond. Cytidine is a component of RNA. If cytosine is attached to deoxyribose ring, he is known as a deoxycytidine.

                                               

Guanosine

Guanosine is a purine nucleoside composed of guanine attaches to a ribose ring via a β-n 9 -glycosidic bond. Guanosine can be phosphorylated by become guanosine monophosphate, cyclic guanosine monophosphate, guanosine diphosphate and guanosine tr ...

                                               

Inosine triphosphate

Inosine triphosphate is an intermediate in the path of the purine metabolism, was seen in the synthesis of ATP and GTP. It includes inosine nucleotide containing three phosphate groups esterified to the sugar fragment.

                                               

8-Oxo-2-deoxyguanosine

8-oxo-2-deoxyguanosine is oxidized derivative of deoxyguanosine. 8-oxo-dG is one of the major oxidation products of DNA. The concentration of 8-oxo-DG within a cell, measurement of oxidative stress.

                                               

Wybutosine

In biochemistry, wybutosine is a highly modified nucleoside inhibitor of RNA phenylalanine transfer which stabilizes the interaction between the codons and anti-codons during protein synthesis. Ensuring accurate protein synthesis is essential for ...

                                               

Zebularine

Zebularine is a nucleoside analog of cytidine. This is a transition state analog inhibitor of cytidine deaminase by binding to the active size as the covalent hydrate. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vi ...

                                               

Curculigoside

Curculigosides are phenols that have been isolated from various plant sources. Curculigoside A, B, C and D can be found in Curculigo orchioides. Curculigoside B can be separated using high-speed countercurrent chromatography. Curculigosides B and ...

                                               

Anthraquinone glycosides

                                               

C-glycoside natural phenols

                                               

Dihydrochalcone glycosides

                                               

Phenol glucuronides

                                               

Phenolic acid glycosides

                                               

Phenylpropanoid glycosides

                                               

Stilbenoid glycosides

                                               

Flavonoid rhamnosides

                                               

Flavonoid rutinosides

                                               

Erythrose

Erythrose is a tetrose sugar with the chemical formula c 4 hours 8 hours 4. It has one aldehyde group and is therefore part of the family alidosi. The natural isomer is D-erythrose. Erythrose was first isolated in 1849 rhubarb French chemist Loui ...

                                               

Threose

Threose is composed of four carbon monosaccharide with a molecular formula with 4 N 8 O 4. It has the aldehyde group of the terminal, not a ketone in its linear chain, and so is part of the family alidosi of monosaccharides. The threose name can ...

                                               

Apiose

Apiose branched sugar chain as residues in galacturonans-type pectins that occurs in parsley and many other plants. Apiose is a component of the cell wall polysaccharides. Apiose 1-reductase uses D-apiitol and NAD for the production apiitol-apios ...

                                               

Arabinose

Arabinose is an aldopentose – a monosaccharide containing five carbon atoms including the functional group of aldehydes. For biosynthetic reasons, most of the carbohydrates are almost always more abundant in nature as the D "-form, or structurall ...

                                               

Lyxose

Lyxose is an aldopentose - a monosaccharide containing five carbon atoms including the functional group of aldehydes. It has the chemical formula 5 H 10 o 5. Its the C-2 epimer of carbon xylose sugar. Lyxose is a rare phenomenon in nature, for ex ...

                                               

Xylose

Xylose is a sugar first isolated from wood, and them for that. Xylose is classified as a monosaccharide of the aldopentose type, which means it contains five carbon atoms and includes an aldehyde functional group. It is derived from hemicellulose ...

                                               

Ribulose

Ribulozo is a ketopentose - a monosaccharide containing five carbon atoms, and including a ketone functional group. It has the chemical formula 5 H 10 o 5. Two enantiomers are possible, d -ribulozo and L-ribulozo. d-Ribulozo is a diastereomer of ...

                                               

Xylulose

Xylulose is a ketopentose, a monosaccharide containing five carbon atoms, and including a ketone functional group. It has the chemical formula 5 H 10 o 5. In nature it occurs as L - and D-enantiomers.

                                               

Aldohexose

                                               

Psicose

D-Psicose, also known as D-allulose, or just allulose, low calorie sugar, a monosaccharide is used in some large commercial producers of food products and beverages. First identified in wheat more than 70 years ago, allulose is naturally present ...

                                               

Mannoheptulose

Mannoheptulose is a heptose, a monosaccharide with seven carbon atoms, and ketosis, with the characteristic carbonyl group of carbohydrates present on a secondary carbon. The form of the sugar alcohol known as mannoheptulose perseitol.

                                               

Sedoheptulose

Sedoheptulose or D - altro -heptulose is ketoheptose - a monosaccharide with seven carbon atoms and a ketone functional group. This is one of the few heptoses in nature and found in various fruits and vegetables ranging from carrots and leeks, fo ...

                                               

SIGLEC

Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of I-type lectins. There are 14 different Siglecs mammals, providing a variety of functions based on the receptor-li ...

                                               

Alpha-keratin

Alpha-keratin or α-keratin, a type of keratin in vertebrates. This protein is a major component of hair, horns, claws, mammal, nails and epidermis layer of the skin. α-keratin is a fibrous structural protein, i.e. it consists of amino acids that ...

                                               

Beta-keratin

β-keratin or beta-keratin is a family member of a structural protein found in the epidermis of reptiles and birds. the β-keratins were named so because they are an integral part of the epidermal stratum corneum is rich in stacked β pleated sheets ...

Encyclopedic dictionary

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Pino - logical board game which is based on tactics and strategy. In general this is a remix of chess, checkers and corners. The game develops imagination, concentration, teaches how to solve tasks, plan their own actions and of course to think logically. It does not matter how much pieces you have, the main thing is how they are placement!

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